PC 1992 - prostate cancer - analysis details:
endpoints, steering files and strata for each overview
[Return to the Contents
List]
Contents List
PC
1992 run-time diktats
-
Run-time estimation of unknown randomisation
date
-
Set randomisation date to the earliest known
date of:
-
Today
-
Cutoff date (if any)
-
LFU/death date
-
Run-time estimation of unknown endpoint/censoring
date
-
Set endpoint/censoring date to:
-
Run-time application of cut-off date, where
relevant
-
If the randomisation date is later than the
cut-off date, omit the case.
-
If the endpoint/censoring date is after the
cut-off date, censor at the cut-off date instead.
-
Run-time estimation of unknown entry age
(except for the age-stratified analysis)
List
of PC 1992 endpoints
|
Endpoint |
Mnemonic |
Trial inclusion criteria |
| 1 |
MORTALITY |
DD |
|
| 2 |
PROSTATE CANCER MORTALITY |
DDPC |
death cause |
| 3 |
MORTALITY FROM NON-PROSTATE-CANCER CAUSES |
NONPC |
death cause |
| 4 |
MORTALITY FROM UNKNOWN CAUSES |
DDUK |
|
| 5 |
MORTALITY FROM IATROGENIC CAUSES |
IATRO |
death cause |
| 6 |
MORTALITY FROM SECOND PRIMARY CANCER |
DDPP |
death cause |
| 7 |
CARDIOVASCULAR MORTALITY |
CVASC |
death cause |
| 8 |
MORTALITY FROM PROSTATE CANCER OR UNKNOWN
CAUSES |
DDPCUK |
|
| 9 |
MORTALITY OMITTING DEATHS FROM NON-PROSTATE-CANCER
CAUSES = (DD - NONPC) |
DDPOSTREC |
|
PC
1992 endpoint definitions (should be read in conjunction with Diktats)
PLEASE NOTE THAT
THIS ENTIRE SECTION IS OUT OF DATE AND IS AWAITING A COMPLETE RE-WRITE!!!
Run-time strategy for data errors
Although efforts are made to create and maintain
an 'error-free' database, numerous minor logical inconsistencies may persist
during correspondence with trialists.
DD: MORTALITY
An event is taken to have occurred if:
The event date is taken as the date died.
If an event is not taken to have occurred,
the case is censored at the date last traced.
List
of PC 1992 strata
|
Stratification |
Mnemonic |
Structure |
| 0 |
Unstratified |
0 |
|
| 1 |
Entry Age |
50 |
|
Stratum |
Abbreviation |
| 1 |
Entry age less than 50 |
Age < 50 |
| 2 |
Entry age 50 or more |
Age 50+ |
|
| 2 |
Entry Age |
A |
|
Stratum |
Abbreviation |
| 1 |
Entry age less than 65 |
Age < 65 |
| 2 |
Entry age 65 - 74 |
Age 65 - 74 |
| 3 |
Entry age 75 or more |
Age 75+ |
| 4 |
Entry age unknown |
Age unknown |
|
| 3 |
Disease Stage |
S |
|
Stratum |
Abbreviation |
| 1 |
M- |
M- |
| 2 |
M+ |
M+ |
| 3 |
Stage unknown |
M? |
|
| 4 |
Tumour Stage |
T |
|
Stratum |
Abbreviation |
| 1 |
T0 |
T0 |
| 2 |
T1 |
T1 |
| 3 |
T2 |
T2 |
| 4 |
T3 |
T3 |
| 5 |
T4 |
T4 |
| 6 |
Stage unknown |
Stage unknown |
|
[Return to the Contents
List]
[End of document, updated to 3 June 2000]